John Manning, the physician aboard the large privateer schooner Mammoth, kept this volume during the ship's voyage from Portland, Maine, to the Madeira Islands and Cape Verde region during the War of 1812. Entries range from December 30, 1814, to April 13, 1815, when the ship returned to New York. The volume lists the patients' names, symptoms, and treatments, as well as occasional notes on weather conditions, locations, and activities, such as the note, "5 Men of War in chase" on February 5, 1815.
Examples of some of the ailments treated include respiratory illnesses, venereal diseases, stomach complaints and colic, headaches, pain and sprains, frostbite, boils and abscesses, dizziness, ague, and wounds. One partial medical exemption for John Schwartze of Capt. Thomas Simmons' Company of Militia, dated May 6, 1816, from Waldoboro, Maine, appears at the end of the volume. An undated list of twenty exempt men and their medical conditions is written on the back cover.