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The Manuscript Sheet Music collection is made up of manuscript music scores, correspondence, and composers' autographs.

The Manuscript Sheet Music collection (approximately 140 items) contains manuscript music scores and composers' autographs, as well as correspondence and other items.

The bulk of the collection is comprised of around 80 music scores, which range in length from one line to several pages; some are complete works, and some are fragments. Most of the brief melodies are accompanied by the composers' signatures and may have been intended as autograph gifts. The longer works are mainly piano and/or vocal scores, and some include lines for violin with piano accompaniment. Lyrics, when present, are written in English and German. Some of the scores are dated and signed, and a few were written in German cities. The cover of the score for "Barcarola" includes an engraving of "The Great Western crossing the Atlantic," and Harry Keyser's "Two Etudes for Pianoforte" is accompanied by a letter by the composer. A manuscript music book belonging to "Th. Hämb, Junior" contains several short pieces with lyrics in a Nordic language.

Additional autographed items include 25 autograph cards, 8 autograph musical quotations, 10 sheets of paper (some with inscriptions), and a photograph of violinist A. Rivarde. Many of the autographed cards, which are the size of business cards or visiting cards, are dated at Chicago in the mid- to late 1880s. The collection's 8 letters (in English, German, and Italian) include one man's opinion of a performance of "Wanda" and a letter illustrated with lines of music. Additional items are a program for a Manchester, New Hampshire, performance of the comic opera Jonah, an ink drawing of a decaying stone building, and lines of poetry or musical lyrics.

The Peter C. Meengs collection is made up of letters, documents, financial papers, notes, printed and ephemeral items, and photographs related to Dr. Meengs's courtship with Sarah "Sallie" Josephine Hall; medical education at Rush Medical College, 1889-1891; his subsequent medical practice in Holland, Eastmonville, and Coopersville, Michigan; and his 1896 patent of a Rectal Irrigating Dilator.

The Peter C. Meengs collection is made up of 38 letters, 15 documents and financial papers, two notebooks, 41 printed and ephemeral items, and 38 photographs related to Dr. Meengs's medical education at Rush Medical College; his subsequent medical practice in Holland, Eastmonville, and Coopersville, Michigan; and his 1896 patent of a Rectal Irrigating Dilator.

The Correspondence includes 38 letters from Peter C. Meengs's to "Sallie," Sarah Josephine Hall, dating between 1885 and 1887. At the time, Sallie attended the Sherman Female Institute at Sherman, Texas, and Meengs lived in Bolivar, Texas. The letters begin with Meeng's request to open a correspondence. He wrote about the activities and marriages of friends; Hall's schooling; her apparent unhappiness at the Sherman Female Institute and his own desires for her not to continue her education; and increasingly his love and affection. On February 8, 1886, remarked that he agrees with her on her sentiments respecting the equality of the sexes. Meengs wrote several letters with phonetic spelling and in a disguised hand, signing them "Sub silentio."

The Documents and Financial Papers series includes 15 certificates, receipts, medical school case studies, and fragments, plus documents related to Peter Meengs's Rectal Irrigating Dilator patent, October 4, 1896. The patent documents include a printing specimen from patent lawyers Barber & Stone, and one signed vellum and three printed copies of the patent.

The Notebooks include one of Peter Meengs's student notebooks from his time at Rush Medical College, and one unused, pre-printed "Physician's Perfect Call List and Record" bearing Peter Meengs's name.

The Printed Items and Ephemera includes 29 items related to Peter Meengs's medical education, 1889-1892, and 12 items pertinent to his medical practice, 1893-1903. They include Rush Medical College ephemera, such as time cards, attendance cards, verification of completion cards, physiology examination questions, a printed notification of the completion of Meengs's doctorate, and 15 extracted pages from Samuel Potter's A Compend of Human Anatomy (1890) bearing ink notes. The materials pertinent to Meengs's practice include his own and other persons' business cards and pre-printed blank scripts, and one 4-page advertisement "Murphy's Button for Anastomosis of the Hollow Viscera" (Chicago).

The Photographs are predominantly identified portraits of Peter C. Meengs and his immediate family and in-laws. The photographs include 16 cabinet cards, 17 cartes-de-visite, one tintype of Meengs standing with another man, one mounted print of Peter Meengs standing in front of his home with two children, two unmounted prints showing Peter Meengs and his siblings, and one negative. Several photographs depict Sarah Hall's classmates at the Sherman Female Institute, including one group portrait of her class.