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This collection is made up of letters that George C. Palmer wrote to his brother Cassius while working at the Michigan Asylum for the Insane in Kalamazoo, Michigan, in the 1860s. Palmer discussed the possibility of becoming an army surgeon, his brother's medical education, and his work in Kalamazoo.

This collection is made up of letters that George C. Palmer wrote to his brother Cassius while working at the Michigan Asylum for the Insane in Kalamazoo, Michigan, in the 1860s. In his first letter (August 21, 1864), Palmer mentioned the upcoming draft and considered the possibility of becoming an army surgeon. He asked Cassius about his intent to study medicine in New York City or at the University of Michigan and encouraged him to remain diligent in his studies. Palmer's final two letters (August 31, 1865, and October 14, 1868) pertain to his work at the asylum, where he had taken on clerical duties alongside his regular medical work; his brother's illness, which prevented Cassius from attending college right away; and his desire to assist in dealing with a monument, despite having procrastinated due to grief.