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The Brimblecom family papers are made up of letters that Massachusetts preacher Samuel Brimblecom and his son, Samuel A. Brimblecom, wrote in the early and mid-19th century. The elder Brimblecom discussed his studies at Harvard in the late 1810s, and his son often wrote of his voyages with the merchant marine to India and China in the 1840s.

The Brimblecom family papers are made up of letters that Massachusetts preacher Samuel Brimblecom and his son, Samuel A. Brimblecom, wrote in the early and mid-19th century. The elder Brimblecom discussed his studies at Harvard in the late 1810s, and his son often wrote of his voyages with the merchant marine to India and China in the 1840s.

The earliest items primarily consist of letters from Samuel Brimblecom to his sister Mary, which he wrote during his time as a student at Harvard University and during the decade following his graduation. He often included his philosophical musings about a variety of topics, including metaphysics and religion, and described his life at school, as a private tutor in South Carolina, and a young preacher in Massachusetts and Maine. Brimblecom continued to write to Mary over the years with updates on his family, but after 1840 his son, Samuel A. Brimblecom, wrote the majority of the correspondence.

Though he often discussed his daily life and acquaintances in Lynn, Massachusetts, Samuel A. Brimblecom also wrote to his parents and siblings about his travels to Asia. In one letter, he copied a poem dedicated to his mother: "Mother, I'm for the Indies Bound" (January 4, 1841). In letters written throughout 1844, he related his experiences in East Asian cities such as Whampoa, Canton, Macao, Singapore, and Calcutta, and noted the practices of businessmen and local customs. On June 27, 1844, for example, he shared his impressions of the region surrounding Bombay, India.

This collection contains letters from Susan Channing to her son William H. Channing, a prominent Unitarian Religious leader in America during the 1840s, 1850s, and 1860s. Also included are letters from relatives and friends of deceased Civil War soldiers, sent to Channing while he was stationed as chaplain at the Stanton Hospital in Washington D.C.

The William H. Channing collection is comprised of 34 letters. Many of these were written by William Henry Channing's mother, Susan Channing, who lived in Brattleboro, Vermont. She reported family events and illnesses, expressed her dismay at her son's letter writing habits, and wrote of her concerns for her son and his family. In a letter dated November 8, 1845, she encouraged William to leave a copy of his papers in a safe place and to consider purchasing a life insurance policy, for which she offered to pay. In an 1847 letter, Susan mentioned the publication of the first volume of Channing's memoirs. In later letters, she described her growing interest in politics and in reading newspapers.

An 1843 letter from J.D. Channing to Susan Channing describes the meetings of a new "church of united brethren and Christian friends," organized in New York by William Russell, at which William H. Channing preached. The letter also mentions Ralph Waldo Emerson's attendance at the meeting and his visit afterwards.

During the Civil War, Channing served as the chaplain of Stanton Hospital. There he received five letters from relatives and friends of deceased soldiers thanking Channing for his kind letters.