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Dr. H. A. Bolles of Cortland, New York, copied medicinal recipes into this volume in or around 1876.

Dr. H. A. Bolles of Cortland, New York, copied recipes for medical treatments in this volume in or around 1876 (the volume contains 300 pages, over half of which are used). Many of the entries are arranged alphabetically by ailment, and some illnesses have multiple suggested treatments and cures. A few recipes are attributed to other doctors and outside sources such as a volume of Materia Medica. The book contains syrups and other mixtures intended to treat chronic conditions, diseases, and afflictions such as acne and baldness. The first few pages include instructions for working with cocaine, converting older medical measurements, and producing an aphrodisiac. One of these notes cautions against mixing chrome acid and glycerin on account of the risk of explosion. A recipe in the back of the volume purports to "remove all bad odors." A few late pages contain lists of medical substances and the ailments they may be used to treat, as well as notes regarding the use of oxygen gas and nitrous oxide. A clipping from The OD Quarterly concerns a method for testing the acidity of urine and recommended dietary guidelines for those suffering from uric acid, gravel, gout, or rheumatism.

M. B. Hartzell, a physician working in Philadelphia, Pennsylvania, maintained this memoranda and account book between 1878 and 1880. He kept notes on poisons and their antidotes, recorded patients' names, addresses, and number of physician visits, and documented charges and payments. He occasionally wrote notes about medical literature to read and what appears to be case notes and medicines prescribed. He tended wounds, abscesses, and burns, treated venereal diseases, performed gynecological and obstetrical services, and gave vaccinations, among other services.

M. B. Hartzell, a physician working in Philadelphia, Pennsylvania, maintained this memoranda and account book between 1878 and 1880. He kept notes on poisons and their antidotes, recorded patients' names, addresses, and number of physician visits, and documented charges and payments. He occasionally wrote notes about medical literature to read and what appears to be case notes and medicines prescribed. He tended wounds, abscesses, and burns, treated venereal diseases, performed gynecological and obstetrical services, and gave vaccinations, among other services.

At least two entries appear to be related to African American patients (October 9-10, 1878, and August 26-27, 1879). A blank prescription slip is laid into the volume, and notes at the end of the volume list out obstetrical cases, document children to be vaccinated, and provide recipes for prescriptions. A circular diagram is drawn on the rear paste down, with notations of calendar dates and a record of numbers for each month, possibly related to tallying medical cases for the year but further research is needed.