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This collection is primarily made up of typescripts of letters that Dr. James M. Holloway wrote to his wife Anne while serving as a Confederate Army surgeon during the Civil War. Additional materials include typescripts on 19th-century medicine and clippings including full-color illustrations, from The Philadelphia Inquirer (1959-1961).

This collection (0.25 linear feet) is made up of typescripts related to Dr. James M. Holloway's service as a Confederate Army surgeon during the Civil War, typescripts related to 19th-century medicine, and illustrated newspaper clippings related to United States Army uniforms, national coats of arms, and Philadelphia, Pennsylvania, during the Civil War.

The bulk of the collection consists of Typescripts, including approximately 121 letters that Holloway wrote to his wife Anne on January 7, 1861, and from July 25, 1861-September 5, 1864. His earliest letters recount his experiences as a surgeon with the 18th Mississippi Infantry Regiment in Virginia, including his treatment of the wounded from the Battle of Ball's Bluff. Holloway, who took pride in his medical career, occasionally described specific patients, including amputees, a woman whose head had become detached from her body, and a dead soldier he dissected. He continued to write about his medical work after being promoted to the command of the hospitals of Richmond, Virginia, in 1862, and also discussed other aspects of his life there, such as the cost of food and other goods. Holloway expressed his devotion to the Confederate cause, and his early letters refer to his commitment to Christianity, which he maintained throughout the remainder of his correspondence. Some of Holloway's letters refer to the movements of Union and Confederate troops in Virginia and the western theater, the possibility of European intervention, specific battles, and the general progress of the war. By the fall of 1864, he feared that Richmond would be cut off from the rest of the Confederacy. In one late letter (written after the Emancipation Proclamation), he advised his wife to sell a female slave.

Holloway wrote 3 letters to his wife in May 1865, expressing his fear that the North would seek retribution from Southerners; he also reported that Beverly Tucker's home had been searched as a result of his suspected connection to the Lincoln assassination. In August and October 1865, Holloway wrote 3 letters to his wife from Louisville, Kentucky, primarily about local churches. Holloway's Civil War correspondence is followed by typescripts of his presidential address to the Tri-State Medical Society (or Mississippi Valley Medical Association) regarding current medical and surgical advancements and the increasing popularity of homeopathy (1882), a partial article about the history of medical education in the South (undated), and an obituary for Samuel Wilcox Warren (January 1878). He wrote 2 additional letters from Amsterdam, Netherlands, and Berlin, Germany, in September 1898, regarding his observations of local hospitals and medical procedures.

The Printed Items series (4 items) contains 3 full-color inserts from issues of The Philadelphia Inquirer, including photographs of toy soldiers wearing historical United States Army uniforms (July 5, 1959); a map of Civil War-era Philadelphia showing the locations of military camps and hospitals (July 5, 1959); a photograph of the coat of arms of the United Kingdom (February 7, 1960); and an editorial commemorating the centennial of the Star of the West incident (January 9, 1961).

This volume contains medical essays composed at the Pennsylvania Hospital in Philadelphia in 1849 and 1850, as well as drafts of letters composed in 1878 and 1879. Essay topics include examinations of specific cases, information on various ailments, notes on surgical operations, and descriptions of medicines.

This volume (162 pages) contains medical essays composed at the Pennsylvania Hospital in Philadelphia in 1849 and 1850, as well as drafts of letters composed in 1878 and 1879. The first 99 pages consist of medical notes and essays written during Carson's final year studying medicine at the University of Pennsylvania, including reports on medical cases, information on ailments and medicines, and notes concerning surgical operations. Essays on ailments and medicines (pages 100-159) focus on symptoms and relief, and include several based on particular types of medicines, such as diuretics and expectorants. Other essays examine the effects of the medicines on the body. The volume also contains medicinal recipes (pp. 160-161). Several doctors are mentioned, including H. S. Patterson, Joseph Carson, G[eorge] B. Wood, and Henry H. Smith. The medical content dates from March 15, 1849, to January 1850, and covers most of the volume's odd-numbered pages, with additional content appearing on some even-numbered pages, including several rough sketches of generic human figures that appear on the inside of both covers and throughout the book, and a series of indexes of miscellaneous words. Some additional items are signatures for residents of several towns in New York, a poem entitled "Buccaneer Bride" (p. 42), recipes for breakfast rolls and doughnuts (pp. 46, 48), household accounts for decorative items, and drafts of letters. Of the letters, one is signed by Grace Burton of Millport, New York. Addie A. McCurdy, also of Millport, New York, occasionally signed her name on some of the even-numbered pages.